Unique Autopure Pilot600 is a benchtop chromatography system for pi lot scale chromatography process. GMP or non - GMP configurations are available. The system has a wide range of working flow, pressure resistance and detection range, which can meet the requirements of process scale - up and small-scale GMP production.
● Unique AutoPure Pilot600 has flexible configuration options, supports chromatography column of 26mm- 200mm in diameter.
● Compact and easy to move. Easy to operate with all functional components located on the front of the device.
● User-friendly intuitive software design, easy to operate and method editing.
● High-precision and large-flow plunger pump ensures a stable flow rate and gradient, which can cover a variety of small-scale, pilot-scale and small-scale production chromatography process.
● Accurate online detectors—fixed or variable wavelength UV detector, conductivity and pH, monitor and record various data of each run.
● Software with audit trail, user management, e- signature, data analysis and report functions to meet the 21 CFR part11 requirements.
Unique AutoPure Pilot600 is controlled by the powerful Unique CDSystem chromatography workstation , equipped with brand computer , with friendly interface, intelligent programming, and easy to operate.
● System control
Real- time online monitoring and control, visual flow diagram, make each operation Intuitively visible, shortcut commands is integrated into the flow diagram to make the operation more simple and faster.
● Method editing
Convenient and reliable human- machine interaction interface , easy to create Methods with pre-programmed phases. You can drag and drop phase modules To program a method, which is convenient for editing and overview. The edited Phase module and methods can be saved as a customized phase module or Methods.script editing is available to support more automatic and customized Method editing.
● Result analysis
Provides comprehensive analysis functions such as Chromatogram comparison, peak integration, and result Export, etc.
● Data storage
Support sql server database, remote data storage, Automatic backup to ensure data security;
● Audit trail
Multi- level user management mode, electronic signature, instrument and data Operation record tracking, complies with gmp/glp, 21 cfr part11, etc.
Unique Autopure Pilot600 comes with standard configuration and also possible to upgrade the modules and change the configuration according to your requirement. The system configuration can be updated by simply adding or removing the modules. Autopure Pilot 600 non - GMP models are provided with general product documentation and operating instructions,with validation documentation available upon request.Sanitary-grade equipment is available that meets the GMP environment. The final equipment configuration is determined when the order is confirmed. The liquid contact parts in the flow path are made of sanitary - grade bio-inert materials that meet the GMP standard to ensure that the liquid flows through.
● Confifiguration model
● Confifiguration introduction
● System basic parameters
| Main system size | L*W*H 600x500x850mm |
| Main system weight | 65kg |
| Control System | Unique CDSystem |
| Enclosure rating | IP54 |
| Electricity supply | 100 ~ 240 V, 50 ~ 60 Hz |
| working environment | Temperature: 4℃- 35℃, Relative Humidity: 20%- 95%, no condensation |
● System performance parameters
System pump (Dual pump system) | A/B pump Flow rate range: 4 - 600ml/min (2-pump packing mode: 1 - 1200ml/min) Eligibility range: 5%-95% Pressure range: 0 - 2MPa (20bar, 290 psi) Viscosity: 0.7 - 10 cp | |
UV detector | 280nm fixed wavelength detector LED light source, lifespan>8000h Detection range: -6— +6AU Linearity: between ±2%@0-2AU Wavelength Accuracy: ±2nm Wavelength Repeatability: ±1 nm Noise: ±1*10 -4 AU (1S) | DAD full spectrum direct reading detector, 200 - 400nm variable dual wavelength. Wavelength Accuracy: ±2nm Wavelength Repeatability: ±1 nm Noise: ±1*10 -4 AU (@254nm, 1S) |
Optical fiber conduction, external flow cell, avoid light source temperature affecting the activity of protein samples, double beam design with high stability. Standard flow cell: 2mm optical diameter, 20ul flow cell volume, maximum pressure resistance 2Mpa | ||
Conductivity detector | Detection range: 0.1mS/cm - 999.9mS/cm Detection cell volume: 20ul Accuracy: ±3% or 0.2mS/cm; built-in temperature sensor, automatic compensation calibration | |
Temperature detector | Temperature Range: 0 - 99 ℃; Temperature Accuracy: ± 2℃at 2℃ – 50℃ | |
PH detector | Detection range: 2 - 12; Accuracy: ± 0.15 | |
Inlet options | 4 inlets for single pump A total of 8 inlets of double pumps Expandable to 12 inlets | |
Outlets options | Maximum 8 | |
Column valve | single column | |
Bubble trap | Effectively remove air bubbles in the system, optional online or offline | |
Mixer | Mixing chamber volume: 12ml | |
Bubble sensor | Support up to 3 | |
Pressure Sensor | One after each pump(A,B), one before the column, one after the column, a total of four, detection range is 0 - 2MPa | |
Online filter | Integrated into mixing cell, pore size, guard column | |
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