For large scale oligonucleotide synthesis, the Phosphoramidite method is the most widely used method, which is a kind of solid phase synthesis
2022-7-14Nucleotide is (biochemistry) the monomer comprising DNA or RNA, while oligonucleotide is a short sequence of nucleotides (rna or dna), typically with twenty or fewer base pairs.
2022-7-14Oligonucleotides are short nucleic acid polymers which are usually made up of 13 to 25 nucleotides and are designed to hybridize specifically to DNA or RNA sequences, while poly usually refers to larger ones.
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